C2 monoclonal antibody (M15), clone 2C11
产品名称: C2 monoclonal antibody (M15), clone 2C11
英文名称: C2 monoclonal antibody (M15), clone 2C11
产品编号: H00000717-M15
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant C2.
- Immunogen:
- C2 (NP_000054.2, 21 a.a. ~ 243 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- APSCPQNVNISGGTFTLSHGWAPGSLLTYSCPQGLYPSPASRLCKSSGQWQTPGATRSLSKAVCKPVRCPAPVSFENGIYTPRLGSYPVGGNVSFECEDGFILRGSPVRQCRPNGMWDGETAVCDNGAGHCPNPGISLGAVRTGFRFGHGDKVRYRCSSNLVLTGSSERECQGNGVWSGTEPICRQPYSYDFPEDVAPALGTSFSHMLGATNPTQKTKESLGR
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgG2a Lambda
- Storage Buffer:
- In 1x PBS, pH 7.2
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- MSDS:
- Download
- Application Image
- ELISA
- Entrez GeneID:
- 717
- GeneBank Accession#:
- NM_000063.3
- Protein Accession#:
- NP_000054.2
- Gene Name:
- C2
- Gene Alias:
- CO2,DKFZp779M0311
- Gene Description:
- complement component 2
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Component C2 is a serum glycoprotein that functions as part of the classical pathway of the complement system. Activated C1 cleaves C2 into C2a and C2b. The serine proteinase C2a then combines with complement factor 4b to create the C3 or C5 convertase. Deficiency of C2 has been reported to associated with certain autoimmune diseases and SNPs in this gene have been associated with altered susceptibility to age-related macular degeneration. This gene localizes within the class III region of the MHC on the short arm of chromosome 6. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described in publications but their full-length sequence has not been determined
- Other Designations:
- C3/C5 convertase,OTTHUMP00000029277,OTTHUMP00000062690,complement C2,complement component C2
- Related Disease
- Atherosclerosis
- Autoimmune Diseases
- Birth Weight
- Calcinosis
- Cardiovascular Diseases
- Choroid Diseases
- Choroidal Neovascularization
- Coronary Aneurysm
- Coronary Artery Disease
- Coronary Disease
- Crohn's disease
- Cross Infection
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Disease Models, Animal
- Disease Progression
- Diseases in Twins
- Edema
- Genetic Predisposition to Disease