SGSH抗体-抗体-抗体-生物在线
上海信裕生物科技有限公司
SGSH抗体

SGSH抗体

商家询价

产品名称： SGSH抗体

英文名称： SGSHAntibody

产品编号： XY14184-1-

产品价格： null

产品产地： 中国/美国

品牌商标： XYbscience

更新时间： 2023-08-17T09:55:27

使用范围： WB,ELISA,IHC-P,IHC-F,IF

上海信裕生物科技有限公司
  • 联系人 : 徐经理
  • 地址 : 上海市闵行莘庄工业区春东路508号A1-2F
  • 邮编 : 200612
  • 所在区域 : 上海
  • 电话 : 152****8802 点击查看
  • 传真 : 点击查看
  • 邮箱 : shxysw02@163.com
  • 二维码 : 点击查看
进入展台

 SGSH抗体Applications

In-house applications ELISA, IHC, WB     Application not tested? Please see our Guarantee.
Species specificity Human,Mouse,Rat; other species not tested.
Images
Prev1NextView more validation data
  • 14184-1-AP;HEK-293 cellsHEK-293 cells were subjected to SDS PAGE followed by western blot with 14184-1-AP( SGSH Antibody) at dilution of 1:600
  • 14184-1-AP;human pancreas cancer tissueImmunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using 14184-1-AP( SGSH Antibody) at dilution of 1:200 (under 10x lens).
  • 14184-1-AP;human pancreas cancer tissueImmunohistochemistry of paraffin-embedded human pancreas cancer tissue slide using 14184-1-AP( SGSH Antibody) at dilution of 1:200 (under 40x lens).
Positive WB detected in HEK-293 cells, Transfected HEK-293 cells
Positive IHC detected in Human pancreas cancer tissue, human liver cancer tissue
Recommended dilution WB : 1:200-1:2000
IHC : 1:20-1:200
 SGSH抗体Application key: WB = Western blotting, IHC = Immunohistochemistry, IF = Immunofluorescence,
IP = Immunoprecipitation
Product Information
Source Rabbit Purification method Antigen affinity purification
Isotype IgG Storage PBS with 0.02% sodium azide and 50% glycerol pH 7.3. Store at -20oC.
Immunogen Information
Immunogen SGSH fusion protein ag5435 Full name N-sulfoglucosamine sulfohydrolase
Calculated molecular
weight		 57 kDa Observed molecular 
weight		  
GenBank accession 
number		 BC047318 Gene ID (NCBI) 6448
Gene symbol SGSH Synonyms HSS, MPS3A, SFMD, SGSH, Sulfoglucosamine sulfamidase, Sulphamidase
Background SGSH抗体

SGSH(N-sulphoglucosamine sulphohydrolase) is also named as HSS, sulphamidase and belongs to the sulfatase family. Sulfamidase is synthesized as a 62 kDa precursor protein, which is modified with mannose 6-phosphate (M6P) residues, allowing their recognition by mannose-6-phosphate receptors in the Golgi complex and ensuring transport to the endosomal/lysosomal system(PMID:21671382). It catalyzes the third step of degradation of glucosaminoglycans and is required for the degradation of heparan sulphate. Defects in SGSH are the cause of mucopolysaccharidosis type 3A (MPS3A), also known as Sanfilippo syndrome A. SGSH抗体
 SGSH抗体