FITC标记的WASF2抗体
产品名称： FITC标记的WASF2抗体
英文名称： Anti-WASF2/FITC
产品编号： HZ-6243R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-WASF2/FITC Conjugated antibody
FITC标记的WASF2抗体
| 英文名称 | Anti-WASF2/FITC |
| 中文名称 | FITC标记的WASF2抗体 |
| 别 名 | Protein WAVE-2; SCAR 2; SCAR; SCAR2; Verprolin homology domain-containing protein 2; WASF2; WASF2_HUMAN; WASP family protein member 2; WASP-family protein member 2; WAVE 2; WAVE2; Wiskott-Aldrich syndrome protein family member 2; Wiskott-Aldrich syndrome protein family verprolin-homologous protein; DICTYOSTELIUM; WASF2_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Cow, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 54 kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human WASF2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function. The published map location (PMID:10381382) has been changed based on recent genomic sequence comparisons, which indicate that the expressed gene is located on chromosome 1, and a pseudogene may be located on chromosome X. Two transcript variants encoding different isoforms have been found for this gene. Function: Downstream effector molecule involved in the transmission of signals from tyrosine kinase receptors and small GTPases to the actin cytoskeleton. Promotes formation of actin filaments. Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Subunit: Binds actin and the Arp2/3 complex. Interacts with BAIAP2. Component of the WAVE2 complex composed of ABI1, CYFIP1/SRA1, NCKAP1/NAP1 and WASF2/WAVE2. Directly interacts with BRK1. Subcellular Location: Cytoplasm, cytoskeleton (By similarity). Cell projection, lamellipodium (By similarity). Note=At the interface between the lamellipodial actin meshwork and the membrane Tissue Specificity: Expressed in all tissues with strongest expression in placenta, lung, and peripheral blood leukocytes, but not in skeletal muscle. Similarity: Belongs to the SCAR/WAVE family. Contains 1 WH2 domain. Database links: Entrez Gene: 10163 Human Entrez Gene: 242687 Mouse Entrez Gene: 313024 Rat Omim: 605875 Human SwissProt: Q9Y6W5 Human SwissProt: Q8BH43 Mouse Unigene: 469244 Human Unigene: 590909 Human Unigene: 23566 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
这个基因编码a member of the综合征蛋白家族。基因的产物是蛋白质，有multiprotein形式复杂，受体激酶和肌动蛋白的链接。结合到肌动蛋白发生through a C端域verprolin同调所有家庭成员。the multiprotein复为to tranduce信号，涉及改变细胞的形状，运动或功能。the published地图（pmid租赁：10381382）has been changed基于最近的基因组序列比较表明，which that the表达基因是位于染色体1我们，和假基因may be located我们X染色体的不同变体编码两个成绩单have been found for this同工酶的改变基因。