FITC标记的肿瘤坏死因子配体超家族成员18抗体
产品名称： FITC标记的肿瘤坏死因子配体超家族成员18抗体
英文名称： Anti-TNFSF18/FITC
产品编号： HZ-2456R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-TNFSF18/FITC Conjugated antibody
FITC标记的肿瘤坏死因子配体超家族成员18抗体
| 英文名称 | Anti-TNFSF18/FITC |
| 中文名称 | FITC标记的肿瘤坏死因子配体超家族成员18抗体 |
| 别 名 | Tumor necrosis factor ligand superfamily member 18; AITRL; GITRL; hGITRL; TL6; Activation inducible TNF related ligand; AITR ligand ; AITRL; GITR ligand; ; Glucocorticoid induced TNF related ligand; Glucocorticoid induced TNFR related protein ligand; MGC138237; Tumor necrosis factor (ligand) superfamily member 18; GITR Ligand; TNF18_HUMAN. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 神经生物学 信号转导 细胞凋亡 生长因子和激素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 23kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human TNFSF18 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for receptor TNFRSF18/AITR/GITR. It has been shown to modulate T lymphocyte survival in peripheral tissues. This cytokine is also found to be expressed in endothelial cells, and is thought to be important for interaction between T lymphocytes and endothelial cells. [provided by RefSeq]. Function: Cytokine that binds to TNFRSF18/AITR/GITR. Regulates T-cell responses. Can function as costimulator and lower the threshold for T-cell activation and T-cell proliferation. Important for interactions between activated T-lymphocytes and endothelial cells. Mediates activation of NF-kappa-B. Subunit: Homodimer. Homotrimer. Subcellular Location: Cell membrane; Single-pass type II membrane protein. Tissue Specificity: Expressed at high levels in the small intestine, ovary, testis, kidney and endothelial cells. Similarity: Belongs to the tumor necrosis factor family. Database links: Entrez Gene: 8995 Human Entrez Gene: 240873 Mouse Omim: 603898 Human SwissProt: Q9UNG2 Human SwissProt: Q7TS55 Mouse Unigene: 248197 Human Unigene: 276823 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
由该基因编码的蛋白质是属于肿瘤坏死因子（TNF）配体家族的细胞因子。该细胞因子是受体TNFRSF18/AITR/GITR的配体。它已被证明调节T淋巴细胞在外周组织中的存活。这种细胞因子也被发现在内皮细胞中表达，并被认为是重要的T淋巴细胞和内皮细胞之间的相互作用。[由RefSeq提供]。