FITC标记的胸腺素β10抗体
产品名称： FITC标记的胸腺素β10抗体
英文名称： Anti-T Beta 10/FITC
产品编号： HZ-
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-T Beta 10/FITC Conjugated antibody
FITC标记的胸腺素β10抗体
| 称 | FITC标记的胸腺素β10抗体 |
| 别 名 | MIG 12; MIG12; Migration inducing gene 12; Migration inducing protein 12; Ptmb10; TB 10; TB10; Thyb 10; Thyb10; Thymosin beta-10; Thymosin beta 10; TMSB10; TYB10_HUMAN |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 免疫学 生长因子和 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 4.9kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human T Beta 10 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The beta thymosins are a family of related peptides, initially isolated from calf thymus but known to be present in a wide variety of mammalian and other vertebrate cells and tissues. Thymosin beta 4 was the first member of the family to be characterized. Although TMSB4 was initially proposed to be a thymic hormone acting at early stages of T cell maturation, the high concentration of the protein and its mRNA in a number of other tissues and cells, as well as the lack of an identifiable secretory signal sequence, suggested that it had a general function in many cell types. Thymosin beta 10 is closely related in sequence to TMSB4 and is also an actin sequestering protein. Function: Plays an important role in the organization of the cytoskeleton. Binds to and sequesters actin monomers (G actin) and therefore inhibits actin polymerization. Subcellular Location: Cytoplasm, cytoskeleton. Similarity: Belongs to the thymosin beta family. Database links: Entrez Gene: 9168 Human Entrez Gene: 100364435 Rat Entrez Gene: 50665 Rat Omim: 188399 Human SwissProt: P63313 Human SwissProt: Q596K9 Human SwissProt: P63312 Rat Unigene: 446574 Human Unigene: 5983 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. 胸腺素β10同其他胸腺素一样也是多肽类，具有增强细胞免疫功能和调节免疫平衡等作用，胸腺素可使由骨髓产生的干细胞转变为T淋巴细胞，因而可增强细胞免疫功能，对体液免疫的影响甚微。 近年来研究认为：该蛋白于肿瘤转移有关，胸腺素β10在肿瘤转移潜能的增高伴有肌动蛋白多聚体的丢失和微丝结构的解聚,微丝骨架的这种变化与Tβ10的表达增高具有相关性 |
β-胸腺素是一类相关肽，最初从小牛胸腺中分离出来，但已知存在于多种哺乳动物和其他脊椎动物细胞和组织中。胸腺素β4是该家族的第一成员。虽然TMSB4最初被认为是一种在T细胞成熟早期起作用的胸腺，但是在许多其他组织和细胞中高浓度的蛋白及其mRNA，以及缺乏可识别的分泌信号序列，表明它具有一般功能。在许多细胞类型中。胸腺素β10与TMSB4序列密切相关，也是一种肌动蛋白螯合蛋白。