分子量:24 kDa

纯度:>95% as determined by SDS-PAGE.

内毒素:Less than 1.0 EU per μg of the Human APCS, His Tag by the LAL method.

Buffer:50 mM Tris, 150 mM NaCl, pH 7.5

生物活性:

产品特性:Human APCS, His Tag is fused with a polyhistidine tag at the C-terminus, and has a calculated MW of 24 kDa. The predicted N-terminus is His 20. The reducing (R) protein migrates as 26 kDa in SDS-PAGE  due to glycosylation.

产品背景:Serum amyloid P-component (SAP) is also known as Pentraxin 2 (PTX2), APCS, which belongs to the pentaxin family. SAP contains one pentaxin domain. PTX2 is a secreted homopentamer protein which is found in serum and urine. SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits. SAP can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. SAP may also function as a calcium-dependent lectin. SAP has certain sequence homology with C-reactive protein (CRP).