SMAD3 monoclonal antibody, clone AF9F7
产品名称: SMAD3 monoclonal antibody, clone AF9F7
英文名称: SMAD3 monoclonal antibody, clone AF9F7
产品编号: MAB2701
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against recombinant SMAD3.
- Immunogen:
- Recombinant His fusion protein corresponding to human SMAD3.
- Host:
- Mouse
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Purification:
- Ammonium sulfate precipitation
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In HEPES, 150 mM NaCl (50% glycerol, 0.01% BSA, 0.03% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- Western Blot (1:500-1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- GSK-3beta regulates cyclin D1 expression: a new target for chemotherapy.
Takahashi-Yanaga F, Sasaguri T.Cell Signal. 2008 Apr;20(4):581-9. Epub 2007 Oct 23.
- 2.
- Targeting cyclins and cyclin-dependent kinases in cancer: lessons from mice, hopes for therapeutic applications in human.
Lee YM, Sicinski P.Cell Cycle. 2006 Sep;5(18):2110-4. Epub 2006 Sep 15.
- 3.
- Mammalian cyclin-dependent kinases.
Malumbres M, Barbacid M.Trends Biochem Sci. 2005 Nov;30(11):630-41. Epub 2005 Oct 19.
- Entrez GeneID:
- 4088
- Gene Name:
- SMAD3
- Gene Alias:
- DKFZp586N0721,DKFZp686J10186,HSPC193,HsT17436,JV15-2,MADH3,MGC60396
- Gene Description:
- SMAD family member 3
- Omim ID:
- 603109
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein functions as a transcriptional modulator activated by transforming growth factor-beta and is thought to play a role in the regulation of carcinogenesis. [provided by RefSeq
- Other Designations:
- MAD, mothers against decapentaplegic homolog 3,SMA- and MAD-related protein 3,SMAD, mothers against DPP homolog 3,mad homolog JV15-2,mad protein homolog,mothers against decapentaplegic homolog 3
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Anemia, Sickle Cell
- Anemia, sickle cell
- Asthma
- Bacteremia
- Breast cancer
- Breast Neoplasms
- Cleft Lip
- Cleft Palate
- Coronary Artery Disease
- Crohn Disease
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetic Nephropathies
- Genetic Predisposition to Disease
- Graft vs Host Disease
- Head and Neck Neoplasms
- Hypersensitivity