PREX1 polyclonal antibody
产品名称： PREX1 polyclonal antibody
英文名称： PREX1 polyclonal antibody
产品编号： PAB17234
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of PREX1.
- Immunogen:
- A synthetic peptide corresponding to amino acids at internal region of human PREX1.
- Sequence:
- C-ERSNLPTDASTTA
- Host:
- Goat
- Theoretical MW (kDa):
- 186
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:16000)
Western Blot (1-3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Upregulation of PIP3-dependent Rac exchanger 1 (P-Rex1) promotes prostate cancer metastasis.
Qin J, Xie Y, Wang B, Hoshino M, Wolff DW, Zhao J, Scofield MA, Dowd FJ, Lin MF, Tu Y.Oncogene. 2009 Apr 23;28(16):1853-63. Epub 2009 Mar 23.
- Entrez GeneID:
- 57580
- Protein Accession#:
- NP_065871.2
- Gene Name:
- PREX1
- Gene Alias:
- KIAA1415,P-REX1
- Gene Description:
- phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1
- Omim ID:
- 606905
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene acts as a guanine nucleotide exchange factor for the RHO family of small GTP-binding proteins (RACs). It has been shown to bind to and activate RAC1 by exchanging bound GDP for free GTP. The encoded protein, which is found mainly in the cytoplasm, is activated by phosphatidylinositol-3,4,5-trisphosphate and the beta-gamma subunits of heterotrimeric G proteins. [provided by RefSeq
- Other Designations:
- OTTHUMP00000031228,phosphatidylinositol 3,4,5-trisphosphate-dependent Rac exchanger 1
- Gene Pathway