SERPINI2 polyclonal antibody
产品名称： SERPINI2 polyclonal antibody
英文名称： SERPINI2 polyclonal antibody
产品编号： PAB6764
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of SERPINI2.
- Immunogen:
- A synthetic peptide corresponding to internal region of human SERPINI2.
- Sequence:
- C-KGDWKQKFRKEDTQ
- Host:
- Goat
- Theoretical MW (kDa):
- 46.1, 47.4
- Reactivity:
- Human
- Specificity:
- This antibody is expected to recognize both reported isoforms (NP_006208.1, NP_00101230.3.1).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:64000)
Western Blot (0.3-1 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (3 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Isolation and characterization of a novel human pancreas-specific gene, pancpin, that is down-regulated in pancreatic cancer cells.
Ozaki K, Nagata M, Suzuki M, Fujiwara T, Miyoshi Y, Ishikawa O, Ohigashi H, Imaoka S, Takahashi E, Nakamura Y.Genes Chromosomes Cancer. 1998 Jul;22(3):179-85.
- Applications
- Western Blot (Tissue lysate)
- SERPINI2 polyclonal antibody (Cat # PAB6764) (0.3 ug/mL) staining of human pancreas lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 5276
- Protein Accession#:
- NP_006208.1;NP_00101230.3.1
- Gene Name:
- SERPINI2
- Gene Alias:
- MEPI,PANCPIN,PI14,TSA2004
- Gene Description:
- serpin peptidase inhibitor, clade I (pancpin), member 2
- Omim ID:
- 605587
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the serine protease inhibitor (serpin) superfamily made up of proteins which play central roles in the regulation of a wide variety of physiological processes, including coagulation, fibrinolysis, development, malignancy and inflammation. The gene product may have a role in a growth-control, possibly growth-suppressing pathway and, when impaired, may be involved in pancreatic carcinogenesis. The protein is a member of the plasminogen activator inhibitor-1 family, a subset of the serpin superfamily whose members act as tissue-specific tPA inhibitors. Two alternatively spliced transcript variants encoding distinct protein isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- myoepithelium-derived serine protease inhibitor,protease inhibitor 14,serine (or cysteine) proteinase inhibitor, clade I (neuroserpin), member 2,serine (or cysteine) proteinase inhibitor, clade I (pancpin), member 2
- Related Disease