PAKα (E195) Antibody
产品名称: PAKα (E195) Antibody
英文名称: PAKα (E195) Antibody
产品编号: BS1803
产品价格: null
产品产地: USA
品牌商标: Bioworld
更新时间: null
使用范围: WB: 1:500~1:1000 IHC: 1:50~1:200 IF: 1:50~1:200
巴傲得生物科技有限公司
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The serine/threonine kinase Pak1 is an effector of small Rho GTPases, Rac1 and Cdc42. Pak1 complex specifically with Rac1 and Cdc42 in their active GTP bound state, inhibiting their intrinsic GTPase activity leading to their autophosphorylation. It plays an important role in the regulation of cell morphogenesis, motility, mitosis, and angiogenesis and has been implicated in the progression of many cancers