DYNLL1 (Human) Recombinant Protein (P01)
产品名称： DYNLL1 (Human) Recombinant Protein (P01)
英文名称： DYNLL1 (Human) Recombinant Protein (P01)
产品编号： H00008655-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human DYNLL1 full-length ORF ( NP_003737.1, 1 a.a. - 89 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MCDRKAVIKNADMSEEMQQDSVECATQALEKYNIEKDIAAHIKKEFDKKYNPTWHCIVGRNFGSYVTHETKHFIYFYLGQVAILLFKSG
- Theoretical MW (kDa):
- 36.8
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 8655
- GeneBank Accession#:
- NM_003746.2
- Protein Accession#:
- NP_003737.1
- Gene Name:
- DYNLL1
- Gene Alias:
- DLC1,DLC8,DNCL1,DNCLC1,LC8,LC8a,MGC126137,MGC126138,PIN,hdlc1
- Gene Description:
- dynein, light chain, LC8-type 1
- Omim ID:
- 601562
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Cytoplasmic dyneins are large enzyme complexes with a molecular mass of about 1,200 kD. They contain two force-producing heads formed primarily from dynein heavy chains, and stalks linking the heads to a basal domain, which contains a varying number of accessory intermediate chains. The complex is involved in intracellular transport and motility. The protein described in this record is a light chain and exists as part of this complex but also physically interacts with and inhibits the activity of neuronal nitric oxide synthase. Binding of this protein destabilizes the neuronal nitric oxide synthase dimer, a conformation necessary for activity, and it may regulate numerous biologic processes through its effects on nitric oxide synthase activity. Alternate transcriptional splice variants have been characterized. [provided by RefSeq
- Other Designations:
- 8 kDa dynein light chain,cytoplasmic dynein light polypeptide,dynein light chain 1,dynein, cytoplasmic, light polypeptide 1,protein inhibitor of neuronal nitric oxide synthase
- Related Disease