TNFSF8 monoclonal antibody (M01A), clone 2E11
产品名称： TNFSF8 monoclonal antibody (M01A), clone 2E11
英文名称： TNFSF8 monoclonal antibody (M01A), clone 2E11
产品编号： H00000944-M01A
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against a partial recombinant TNFSF8.
- Immunogen:
- TNFSF8 (NP_001235, 153 a.a. ~ 234 a.a) partial recombinant protein with GST tag. MW of the GST tag alone is 26 KDa.
- Sequence:
- NNSVDLKLELLINKHIKKQALVTVCESGMQTKHVYQNLSQFLLDYLQVNTTISVNVDTFQYIDTSTFPLENVLSIFLYSNSD
- Host:
- Mouse
- Reactivity:
- Human
- Isotype:
- IgM Kappa
- Storage Buffer:
- In ascites fluid
- Storage Instruction:
- Store at -20°C or lower. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
Western Blot detection against Immunogen (34.76 KDa) .
- MSDS:
Download
- Applications
- Western Blot (Transfected lysate)
- Western Blot analysis of TNFSF8 expression in transfected 293T cell line by TNFSF8 monoclonal antibody (M01A), clone 2E11.
Lane 1: TNFSF8 transfected lysate (Predicted MW: 26 KDa).
Lane 2: Non-transfected lysate. - Protocol Download
- Western Blot (Recombinant protein)
- Protocol Download
- Application Image
- Western Blot (Transfected lysate)
- enlarge
- Western Blot (Recombinant protein)
- ELISA
- Entrez GeneID:
- 944
- GeneBank Accession#:
- NM_001244
- Protein Accession#:
- NP_001235
- Gene Name:
- TNFSF8
- Gene Alias:
- CD153,CD30L,CD30LG,MGC138144
- Gene Description:
- tumor necrosis factor (ligand) superfamily, member 8
- Omim ID:
- 603875
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. [provided by RefSeq
- Other Designations:
- CD153 antigen,CD30 antigen ligand,CD30 ligand,OTTHUMP00000022762
- Gene Pathway