STAT5A polyclonal antibody
产品名称： STAT5A polyclonal antibody
英文名称： STAT5A polyclonal antibody
产品编号： PAB11810
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of STAT5A.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human STAT5A.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 95
- Reactivity:
- Human
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- Lot specific
- Storage Buffer:
- In 10 mM PBS, pH 7.4 (1% BSA, 0.1% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Quality Control Testing:
- Antibody Reactive Against Synthetic Peptide.
- Recommend Usage:
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (Formalin/PFA-fixed paraffin-embedded sections) (1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 6776
- Gene Name:
- STAT5A
- Gene Alias:
- MGF,STAT5
- Gene Description:
- signal transducer and activator of transcription 5A
- Omim ID:
- 601511
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the STAT family of transcription factors. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. This protein is activated by, and mediates the responses of many cell ligands, such as IL2, IL3, IL7 GM-CSF, erythropoietin, thrombopoietin, and different growth hormones. Activation of this protein in myeloma and lymphoma associated with a TEL/JAK2 gene fusion is independent of cell stimulus and has been shown to be essential for the tumorigenesis. The mouse counterpart of this gene is found to induce the expression of BCL2L1/BCL-X(L), which suggests the antiapoptotic function of this gene in cells. [provided by RefSeq
- Other Designations:
- -
- Interactome
- Related Disease
- Asthma
- Asthma
- Birth Weight
- Breast cancer
- Breast Neoplasms
- Bronchiolitis, Viral
- Carcinoma, Hepatocellular
- Disease Progression
- Genetic Predisposition to Disease
- Glioblastoma
- Glioma
- Hepatitis C
- Infant, Premature, Diseases
- Leukemia
- Leukemia, Myeloid, Acute
- Liver Neoplasms
- Lupus Erythematosus, Systemic
- Meningeal Neoplasms
- Meningioma