CTCF polyclonal antibody
产品名称： CTCF polyclonal antibody
英文名称： CTCF polyclonal antibody
产品编号： PAB19945
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CTCF.
- Immunogen:
- A synthetic peptide corresponding to C-terminus of human CTCF.
- Host:
- Rabbit
- Theoretical MW (kDa):
- 82.8, 150
- Reactivity:
- Human, Mouse
- Specificity:
- This antibody reacts with endogenous CTCF protein. A BLAST analysis was used to suggest reactivity with CTCF from human, mouse, horse, bovine, panda, rabbit, Danio, and chicken based on a 100% homology with the immunizing sequence. Cross-reactivity with CTCF from other sources has not been determined.
- Form:
- Liquid
- Purification:
- Immunoaffinity purification
- Concentration:
- 1.3 mg/mL
- Storage Buffer:
- In 20 mM KH2PO4, 150 mM NaCl, pH 7.2 (0.01% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:200000-1:250000)
Western Blot (1:1000)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Entrez GeneID:
- 10664
- Gene Name:
- CTCF
- Gene Alias:
- -
- Gene Description:
- CCCTC-binding factor (zinc finger protein)
- Omim ID:
- 604167
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the BORIS + CTCF gene family and encodes a transcriptional regulator protein with 11 highly conserved zinc finger (ZF) domains. This nuclear protein is able to use different combinations of the ZF domains to bind different DNA target sequences and proteins. Depending upon the context of the site, the protein can bind a histone acetyltransferase (HAT)-containing complex and function as a transcriptional activator or bind a histone deacetylase (HDAC)-containing complex and function as a transcriptional repressor. If the protein is bound to a transcriptional insulator element, it can block communication between enhancers and upstream promoters, thereby regulating imprinted expression. Mutations in this gene have been associated with invasive breast cancers, prostate cancers, and Wilms' tumors. [provided by RefSeq
- Other Designations:
- 11 zinc finger transcriptional repressor,11-zinc finger protein,CCCTC-binding factor,CTCFL paralog,transcriptional repressor CTCF