FITC标记的EXD3蛋白抗体
产品名称： FITC标记的EXD3蛋白抗体
英文名称： Anti-EXD3/FITC
产品编号： HZ-14655R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-EXD3/FITC Conjugated antibody
FITC标记的EXD3蛋白抗体
| 英文名称 | Anti-EXD3/FITC |
| 中文名称 | FITC标记的EXD3蛋白抗体 |
| 别 名 | EXDL3; EXD3; Exonuclease 3''-5'' domain-containing protein 3; Exonuclease 3'-5' domain containing 3; FLJ20433; HBE269; LOC54932; mut-7; MUT7_HUMAN; Probable exonuclease mut-7 homolog; probable exonuclease mut-7 homolog, isoform 5. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 97kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human EXD3 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: EXD3 is an 876 amino acid protein that contains one 3’-5’ exonuclease domain, suggesting a possible role in nucleotide cleavage. The gene encoding EXDL3 maps to chromosome 9 and is expressed as four isoforms that are produced via alternative splicing events. Chromosome 9 contains 145 million base pairs and comprises 4% of the human genome, encoding nearly 900 genes. Hereditary hemorrhagic telangiectasia, which is characterized by harmful vascular defects, and Familial dysautonomia, are both associated with chromosome 9. Notably, chromosome 9 encompasses the largest interferon family gene cluster. Chromosome 9 is partnered with chromosome 22 in translocations that lead to the aberrant production of a BCR-ABL fusion protein often found in leukemias. Similarity: Belongs to the mut-7 family. Contains 1 3'-5' exonuclease domain. Database links: Entrez Gene: 54932 Human SwissProt: Q8N9H8 Human Unigene: 495553 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
exd3是一个876个氨基酸的蛋白质，包含一个3’5’外切酶域，表明核苷酸裂解作用。编码EXDL3的基因映射到9号染色体上，并被表达为通过选择性剪接事件产生的四种亚型。第9号染色体含有1亿4500万个碱基对，包含4%个人类基因组，编码近900个基因。遗传性出血性毛细血管扩张症，其特点是有害的血管缺陷，和家族性自主神经功能障碍，均与9号染色体相关。值得注意的是，9号染色体包含最大的干扰素家族基因簇。9号染色体与易位，导致一个BCR-ABL融合蛋白经常发现在白血病染色体异常的生产22。