DEFA1/DEFA3 polyclonal antibody
产品名称： DEFA1/DEFA3 polyclonal antibody
英文名称： DEFA1/DEFA3 polyclonal antibody
产品编号： PAB18743
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of DEFA1/DEFA3.
- Immunogen:
- A synthetic peptide corresponding to internal region of human DEFA1/DEFA3.
- Sequence:
- C-DESLAPKHPGSRKN
- Host:
- Goat
- Theoretical MW (kDa):
- 10.2
- Reactivity:
- Human
- Specificity:
- This antibody is expected to equally recognize DEFA1 precursor and DEFA3 precursor.
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.02% sodium azide, 0.5% BSA)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:128000)
Western Blot (1-3 ug/mL)
Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections) (4-6 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Applications
- Western Blot (Tissue lysate)
- DEFA1|DEFA3 polyclonal antibody (Cat # PAB18743) (2 ug/mL) staining of human spleen lysate (35 ug protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence.
- Entrez GeneID:
- 1667
- Protein Accession#:
- NP_004075.1 (Gene ID : 1667);NP_005208.1 (Gene ID : 1668)
- Gene Name:
- DEFA1
- Gene Alias:
- DEF1,DEFA2,HNP-1,HP-1,MGC138393,MRS
- Gene Description:
- defensin, alpha 1
- Omim ID:
- 125220
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 1, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from defensin, alpha 3 by only one amino acid. [provided by RefSeq
- Other Designations:
- OTTHUMP00000196017,defensin, alpha 1, myeloid-related sequence,defensin, alpha 2,myeloid-related sequence
- Entrez GeneID:
- 1668
- Protein Accession#:
- NP_004075.1 (Gene ID : 1667);NP_005208.1 (Gene ID : 1668)
- Gene Name:
- DEFA3
- Gene Alias:
- DEF3,HNP-3,HNP3,HP-3
- Gene Description:
- defensin, alpha 3, neutrophil-specific
- Omim ID:
- 604522
- Gene Ontology:
- Hyperlink
- Gene Summary:
- Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. Several alpha defensin genes appear to be clustered on chromosome 8. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. It differs from defensin, alpha 1 by only one amino acid. [provided by RefSeq
- Other Designations:
- defensin 3, neutrophil-specific,defensin, alpha 3,neutrophil peptide 3