DPABH-28159 recognises the C terminal part of Metabotropic Glutamate Receptor 1 alpha isoform (mGluR1a) but does not recognise the beta isoform (mGluR1b).Receptor for glutamate. The activity of this receptor is mediated by a G-protein that activates a phosphatidylinositol-calcium second messenger system. May participate in the central action of glutamate in the CNS, such as long-term potentiation in the hippocampus and long-term depression in the cerebellum.Shipped at 4°C. Upon delivery aliquot and store at -20°C. Avoid freeze / thaw cycles. *   http://www.creative-diagnostics.com/Anti-GRM1-PAb-208088-147.htm