FITC标记的FBXO44蛋白抗体
产品名称： FITC标记的FBXO44蛋白抗体
英文名称： Anti-FBXO44/FITC
产品编号： HZ-16050R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-FBXO44/FITC Conjugated antibody
FITC标记的FBXO44蛋白抗体
| 英文名称 | Anti-FBXO44/FITC |
| 中文名称 | FITC标记的FBXO44蛋白抗体 |
| 别 名 | 5730411K09; AV001623; DKFZp781J0852; F box gene 3; F box only protein 44; F box only protein 6a; F box protein 44; F box protein FBX30; F box/G domain protein 3; F-box only protein 44; F-box protein FBX30; F-box/G-domain protein 3; FBG3; FBX30; FBX44; FBX44_HUMAN; FBX6A; Fbxo44; Fbxo6a; MGC14140; RGD1562463. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 泛素 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Pig, Cow, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 30kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human FBXO44 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene encodes a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of the ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. The protein encoded by this gene belongs to the Fbxs class. It is also a member of the NFB42 (neural F Box 42 kDa) family, similar to F-box only protein 2 and F-box only protein 6. Four alternatively spliced transcript variants encoding two distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] Function: Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Subunit: Part of a SCF (SKP1-cullin-F-box) protein ligase complex. Interacts with SKP1 and CUL1. Tissue Specificity: Abundantly expressed in brain and kidney. Expressed at lower levels in heart, spleen and liver. Similarity: Contains 1 F-box domain. Contains 1 FBA (F-box associated) domain. Database links: Entrez Gene: 93611 Human Entrez Gene: 230903 Mouse Entrez Gene: 500587 Rat Omim: 609111 Human SwissProt: Q9H4M3 Human SwissProt: Q8BK26 Mouse Unigene: 556006 Human Unigene: 220327 Mouse Unigene: 401783 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic application |
该基因编码的F盒蛋白家族的成员，其特征在于约40个氨基酸基序，F盒。F-box蛋白构成泛素蛋白连接酶复合物SCF(SKP1-cullin-F-box)的四个亚基之一，SCFs在磷酸化依赖性泛素化中起作用。F-box蛋白分为3类：含有WD-40结构域的Fbws，含有富含亮氨酸重复序列的Fbls，以及含有不同蛋白质-蛋白质相互作用模块或没有可识别基序的Fbxs。该基因编码的蛋白属于FBXS类。它也是NFB42（神经F盒42 kDa）家族的成员，与F盒仅蛋白2和F盒仅蛋白6相似。四个交替剪接转录变体编码两种不同的异构体已经发现这个基因。[ RefSeq，JUL 2008 ]