CXCR4 polyclonal antibody
产品名称： CXCR4 polyclonal antibody
英文名称： CXCR4 polyclonal antibody
产品编号： PAB0361
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Rabbit polyclonal antibody raised against synthetic peptide of CXCR4.
- Immunogen:
- A synthetic peptide corresponding to amino acids 328-338 of human CXCR4.
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Form:
- Liquid
- Storage Buffer:
- In PBS (0.05% BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C. For long term storage store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Hypoxia-inducible factor 1 and VEGF upregulate CXCR4 in glioblastoma: implications for angiogenesis and glioma cell invasion.
Zagzag D, Lukyanov Y, Lan L, Ali MA, Esencay M, Mendez O, Yee H, Voura EB, Newcomb EW.Lab Invest. 2006 Dec;86(12):1221-32. Epub 2006 Oct 30.
- 2.
- Stromal cell-derived factor-1alpha and CXCR4 expression in hemangioblastoma and clear cell-renal cell carcinoma: von Hippel-Lindau loss-of-function induces expression of a ligand and its receptor.
Zagzag D, Krishnamachary B, Yee H, Okuyama H, Chiriboga L, Ali MA, Melamed J, Semenza GL.Cancer Res. 2005 Jul 15;65(14):6178-88.
- Application Image
- Western Blot (Cell lysate)
- enlarge
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Entrez GeneID:
- 7852
- Gene Name:
- CXCR4
- Gene Alias:
- CD184,D2S201E,FB22,HM89,HSY3RR,LAP3,LCR1,LESTR,NPY3R,NPYR,NPYRL,NPYY3R,WHIM
- Gene Description:
- chemokine (C-X-C motif) receptor 4
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq
- Other Designations:
- C-X-C chemokine receptor type 4,CD184 antigen,chemokine (C-X-C motif), receptor 4 (fusin),chemokine receptor 4,fusin,leukocyte-derived seven-transmembrane-domain receptor,lipopolysaccharide-associated protein 3,neuropeptide Y receptor Y3,seven transmembra
- Related Disease
- Acquired Immunodeficiency Syndrome
- Breast cancer
- Breast Neoplasms
- Carcinoma, Hepatocellular
- Carcinoma, Squamous Cell
- Cardiovascular Diseases
- Celiac Disease
- Colon cancer
- Colorectal Neoplasms
- Coronary Disease
- Diabetes Mellitus, Type 2
- Disease Progression
- Disease Susceptibility
- Edema
- Genetic Predisposition to Disease
- Growth Hormone-Secreting Pituitary Adenoma
- Hepatitis B
- HIV Infections
- Hyperglycemia