GBA (Human) Recombinant Protein (Q01)
产品名称： GBA (Human) Recombinant Protein (Q01)
英文名称： GBA (Human) Recombinant Protein (Q01)
产品编号： H00002629-Q01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human GBA partial ORF ( NP_000148, 146 a.a. - 235 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- SYFSEEGIGYNIIRVPMASCDFSIRTYTYADTPDDFQLHNFSLPEEDTKLKIPLIHRALQLAQRPVSLLASPWTSPTWLKTNGAVNGKGS
- Theoretical MW (kDa):
- 35.64
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 2629
- GeneBank Accession#:
- NM_000157
- Protein Accession#:
- NP_000148
- Gene Name:
- GBA
- Gene Alias:
- GBA1,GCB,GLUC
- Gene Description:
- glucosidase, beta; acid (includes glucosylceramidase)
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a lysosomal membrane protein that cleaves the beta-glucosidic linkage of glycosylceramide, an intermediate in glycolipid metabolism. Mutations in this gene cause Gaucher disease, a lysosomal storage disease characterized by an accumulation of glucocerebrosides. A related pseudogene is approximately 12 kb downstream of this gene on chromosome 1. Alternative splicing results in multiple transcript variants encoding the same protein. [provided by RefSeq
- Other Designations:
- D-glucosyl-N-acylsphingosine glucohydrolase,OTTHUMP00000033992,OTTHUMP00000033993,glucocerebrosidase,glucocerebrosidase (alt.),lysosomal glucocerebrosidase
- Related Disease
- Alzheimer Disease
- Alzheimer disease
- Bone Diseases, Metabolic
- Cardiovascular Diseases
- Cognition Disorders
- Cystic fibrosis
- Deafness
- Dementia
- Diabetes Mellitus, Type 2
- Disease Progression
- Edema
- Epilepsy
- Essential Tremor
- Essential tremor
- Gaucher Disease
- Gaucher disease
- Genetic Diseases, Inborn
- Genetic Predisposition to Disease
- Hypergammaglobulinemia