FKBP3 (Human) Recombinant Protein
产品名称： FKBP3 (Human) Recombinant Protein
英文名称： FKBP3 (Human) Recombinant Protein
产品编号： P3500
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
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- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human FKBP3 (NP_002004, 1 a.a. - 224 a.a.) full-length recombinant protein expressed in Escherichia coli.
- Sequence:
- MAAAVPQRAWTVEQLRSEQLPKKDIIKFLQEHGSDSFLAEHKLLGNIKNVAKTANKDHLVTAYNHLFETKRFKGTESISKVSEQVKNVKLNEDKPKETKSEETLDEGPPKYTKSVLKKGDKTNFPKKGDVVHCWYTGTLQDGTVFDTNIQTSAKKKKNAKPLSFKVGVGKVIRGWDEALLTMSKGEKARLEIEPEWAYGKKGQPDAKIPPNAKLTFEVELVDID
- Theoretical MW (kDa):
- 25.1
- Form:
- Liquid
- Preparation Method:
- Escherichia coli expression system
- Purification:
- Conventional Chromatography
- Concentration:
- 1 mg/mL
- Purity:
- > 90% by SDS-PAGE
- Activity:
- Specific activity is > 490 nmoles/min/mg, and is defined as the amount of enzyme that cleaves 1umole of suc-AAFP-pNA per minute at 25°C in Tris-HCl pH 8.0 using chymotrypsin.
- Storage Buffer:
- In 20 mM Tris-HCl, pH 8.0 (1 mM dithiothreitol, 10% glycerol)
- Storage Instruction:
- Store at 4°C for 1-2 weeks. For long term storage store at -20°C or -80°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Loading 3 ug protein in 15% SDS-PAGE
- Application Image
- Functional Study
- SDS-PAGE
- Entrez GeneID:
- 2287
- Protein Accession#:
- NP_002004
- Gene Name:
- FKBP3
- Gene Alias:
- FKBP-25,PPIase
- Gene Description:
- FK506 binding protein 3, 25kDa
- Omim ID:
- 186947
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a member of the immunophilin protein family, which play a role in immunoregulation and basic cellular processes involving protein folding and trafficking. This encoded protein is a cis-trans prolyl isomerase that binds the immunosuppressants FK506 and rapamycin, as well as histone deacetylases, the transcription factor YY1, casein kinase II, and nucleolin. It has a higher affinity for rapamycin than for FK506 and thus may be an important target molecule for immunosuppression by rapamycin. [provided by RefSeq
- Other Designations:
- FK506 binding protein 3 (25kD),FK506-binding protein 25, T-cell,FK506-binding protein 3 (25kD),peptidyl-prolyl cis-trans isomerase,rapamycin binding protein,rapamycin-selective 25 kDa immunophilin,rotamase
- Related Disease