FITC标记的富含半胱氨酸分泌蛋白1抗体
产品名称： FITC标记的富含半胱氨酸分泌蛋白1抗体
英文名称： Anti-CRISP1/FITC
产品编号： HZ-14058R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-CRISP1/FITC Conjugated antibody
FITC标记的富含半胱氨酸分泌蛋白1抗体
| 英文名称 | Anti-CRISP1/FITC |
| 中文名称 | FITC标记的富含半胱氨酸分泌蛋白1抗体 |
| 别 名 | Acidic epididymal glycoprotein homolog; Acidic epididymal glycoprotein like 1; AEG like protein; AEG related protein; AEG-like protein; AEGL1; ARP; CRIS1_HUMAN; CRISP-1; CRISP1; Cysteine rich secretory protein 1; Cysteine rich secretory protein 1 delta; Cysteine-rich secretory protein 1; HSCRISP1D; HSCRISP1G; HUMARP; Protein DE like. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 发育生物学 信号转导 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 26kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human CRISP1 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: Fertilization consists of a sequence of specific cell-cell interactions culminating in the fusion of the sperm and egg plasma membranes. Recognition, binding, and fusion occur through the interaction of complementary molecules that are localized to specific domains of the sperm and egg plasma membranes. In the sperm, the postacrosomal region or equatorial segment is involved in sperm-egg plasma membrane fusion. The protein encoded by this gene is a member of the cysteine-rich secretory protein (CRISP) family. It is expressed in the epididymis, is secreted into the epididymal lumen, and binds to the postacrosomal region of the sperm head, where it plays a role in sperm-egg fusion. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2011] Function: May have a role in sperm-egg fusion and maturation. Subcellular Location: Note=Located in the lumen and epithelium of distal ductus efferentes and epididymal ducts, and on the postacrosomal region of the sperm head. Tissue Specificity: Caput, corpus, and cauda regions of the epididymis, the ductus deferens, sperm and seminal plasma. Similarity: Belongs to the CRISP family. Contains 1 SCP domain. Contains 1 ShKT domain. Database links: Entrez Gene: 167 Human Omim: 601193 Human SwissProt: P54107 Human Unigene: 109620 Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. |
受精包括一系列特定的细胞-细胞相互作用，最终导致精子和卵子质膜的融合。识别、结合和融合是通过定位于精子和卵子质膜特定区域的互补分子的相互作用而发生的。在精子中，顶体区或赤道段参与精子卵质膜融合。由该基因编码的蛋白质是富含半胱氨酸的分泌蛋白（CRISP）家族的成员。它在附睾中表达，被分泌到附睾腔中，并与精子的顶体后区结合，在精子-卵子融合中起作用。另一种编码不同的异构体的剪接转录变体已被发现用于该基因。〔RefSeq，2011〕