CYP11A1 (Human) Recombinant Protein (P01)
产品名称： CYP11A1 (Human) Recombinant Protein (P01)
英文名称： CYP11A1 (Human) Recombinant Protein (P01)
产品编号： H00001583-P01
产品价格： 0
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围： null
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Human CYP11A1 full-length ORF ( AAH32329.1, 1 a.a. - 521 a.a.) recombinant protein with GST-tag at N-terminal.
- Sequence:
- MLAKGLPPRSVLVKGCQTFLSAPREGLGRLRVPTGEGAGISTRSPRPFNEIPSPGDNGWLNLYHFWRETGTHKVHLHHVQNFQKYGPIYREKLGNVESVYVIDPEDVALLFKSEGPNPERFLIPPWVAYHQYYQRPIGVLLKKSAAWKKDRVALNQEVMAPEATKNFLPLLDAVSRDFVSVLHRRIKKAGSGNYSGDISDDLFRFAFESITNVIFGERQGMLEEVVNPEAQRFIDAIYQMFHTSVPMLNLPPDLFRLFRTKTWKDHVAAWDVIFSKADIYTQNFYWELRQKGSVHHDYRGILYRLLGDSKMSFEDIKANVTEMLAGGVDTTSMTLQWHLYEMARNLKVQDMLRAEVLAARHQAQGDMATMLQLVPLLKASIKETLRLHPISVTLQRYLVNDLVLRDYMIPAKTLVQVAIYALGREPTFFFDPENFDPTRWLSKDKNITYFRNLGFGWGVRQCLGRRIAELEMTIFLINMLENFRVEIQHLSDVGTTFNLILMPEKPISFTFWPFNQEATQQ
- Theoretical MW (kDa):
- 86.5
- Preparation Method:
- in vitro wheat germ expression system
- Purification:
- Glutathione Sepharose 4 Fast Flow
- Storage Buffer:
- 50 mM Tris-HCI, 10 mM reduced Glutathione, pH=8.0 in the elution buffer.
- Storage Instruction:
- Store at -80°C. Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- 12.5% SDS-PAGE Stained with Coomassie Blue.
- Note:
- Best use within three months from the date of receipt of this protein.
- MSDS:
Download
- Application Image
- Enzyme-linked Immunoabsorbent Assay
- Western Blot (Recombinant protein)
- Antibody Production
- Protein Array
- Entrez GeneID:
- 1583
- GeneBank Accession#:
- BC032329.1
- Protein Accession#:
- AAH32329.1
- Gene Name:
- CYP11A1
- Gene Alias:
- CYP11A,P450SCC
- Gene Description:
- cytochrome P450, family 11, subfamily A, polypeptide 1
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the mitochondrial inner membrane and catalyzes the conversion of cholesterol to pregnenolone, the first and rate-limiting step in the synthesis of the steroid hormones. Two transcript variants encoding different isoforms have been found for this gene. The cellular location of the smaller isoform is unclear since it lacks the mitochondrial-targeting transit peptide. [provided by RefSeq
- Other Designations:
- cholesterol 20-22 desmolase,cholesterol monooxygenase (side-chain cleaving),cytochrome P450, subfamily XIA,cytochrome P450, subfamily XIA (cholesterol side chain cleavage),cytochrome P450C11A1,steroid 20-22-lyase
- Gene Pathway
- Related Disease
- Adenocarcinoma
- Asperger Syndrome
- Autistic Disorder
- Breast cancer
- Breast Neoplasms
- Breast Neoplasms, Male
- Carcinoma, Non-Small-Cell Lung
- Carcinoma, Squamous Cell
- Celiac Disease
- Colorectal Neoplasms
- Disease Progression
- Ductus Arteriosus, Patent
- Endometrial Neoplasms
- Fibrocystic Breast Disease
- Genetic Predisposition to Disease
- Genital Neoplasms, Male
- Hyperandrogenism
- Hypertension
- Infant, Premature, Diseases