FITC标记的前列腺跨膜上皮2抗原抗体
产品名称： FITC标记的前列腺跨膜上皮2抗原抗体
英文名称： Anti-STEAP2/FITC
产品编号： HZ-12824R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
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Rabbit Anti-STEAP2/FITC Conjugated antibody
FITC标记的前列腺跨膜上皮2抗原抗体
| 英文名称 | Anti-STEAP2/FITC |
| 中文名称 | FITC标记的前列腺跨膜上皮2抗原抗体 |
| 别 名 | 4921538B17Rik; AI930049; IPCA 1; IPCA1; Metalloreductase STEAP2; PCANAP 1; PCANAP1; Prostate cancer associated protein 1; Prostate cancer-associated protein 1; Protein up regulated in metastatic prostate cancer; Protein upregulated in metastatic prostate cancer; PUMPCn; Six transmembrane epithelial antigen of prostate 2; Six transmembrane epithelial antigen of the prostate 2; Six-transmembrane epithelial antigen of prostate 2; SixTransMembrane protein of prostate 1; STAMP 1; STAMP1; STEA2_HUMAN; STEAP 2; STEAP family member 2, metalloreductase; Steap2; STMP; UNQ6507/PRO23203. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 肿瘤 细胞生物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Horse, Sheep, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 56kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 2mg/1ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human STEAP2 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: This gene is a member of the STEAP family and encodes a multi-pass membrane protein that localizes to the Golgi complex, the plasma membrane, and the vesicular tubular structures in the cytosol. A highly similar protein in mouse has both ferrireductase and cupric reductase activity, and stimulates the cellular uptake of both iron and copper in vitro. Increased transcriptional expression of the human gene is associated with prostate cancer progression. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. [provided by RefSeq, Jul 2008] Function: Metalloreductase that has the ability to reduce both Fe(3+) to Fe(2+) and Cu(2+) to Cu(1+). Uses NAD(+) as acceptor. Subcellular Location: Endosome membrane. Cell membrane. Tissue Specificity: Expressed at high levels in prostate and at significantly lower levels in heart, brain, kidney, pancreas, and ovary. Similarity: Belongs to the STEAP family. Contains 1 ferric oxidoreductase domain. Database links: Entrez Gene: 504616 Cow Entrez Gene: 261729 Human Entrez Gene: 74051 Mouse Entrez Gene: 312052. Rat Omim: 605094 Human SwissProt: Q8NFT2 Human SwissProt: Q8BWB6 Mouse Unigene: 489051 Human Unigene: 274956 Mouse Unigene: 203614 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
该基因是STEAP家族的成员，编码多通道膜蛋白，定位于细胞质中的高尔基复合体、质膜和囊泡管结构。一种在小鼠体内高度相似的蛋白具有铁还原酶和铜还原酶活性，并刺激细胞在体外对铁和铜的摄取。人类基因的转录表达增加与前列腺癌进展相关。已经鉴定了编码不同异构体的交替转录剪接变异体。[