HNF1A monoclonal antibody, clone 7H3
产品名称： HNF1A monoclonal antibody, clone 7H3
英文名称： HNF1A monoclonal antibody, clone 7H3
产品编号： MAB1813
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against partial recombinant HNF1A.
- Immunogen:
- Recombinant MBP fusion protein corresponding to amino acids 102-269 of human HNF1A.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG
- Storage Buffer:
- In 100 mM Tris-glycine, 150 mM NaCl, pH 7.4 (30% glycerol, 0.08% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Quality Control Testing:
- Antibody Reactive Against Recombinant Protein.
- Recommend Usage:
- The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Tcf-1-mediated transcription in T lymphocytes: differential role for glycogen synthase kinase-3 in fibroblasts and T cells.
Staal FJ, Burgering BM, van de Wetering M, Clevers HC.Int Immunol. 1999 Mar;11(3):317-23.
- 2.
- Ectopic activation of lymphoid high mobility group-box transcription factor TCF-1 and overexpression in colorectal cancer cells.
Mayer K, Hieronymus T, Castrop J, Clevers H, Ballhausen WG.Int J Cancer. 1997 Aug 7;72(4):625-30.
- 3.
- The human TCF-1 gene encodes a nuclear DNA-binding protein uniquely expressed in normal and neoplastic T-lineage lymphocytes.
Castrop J, van Wichen D, Koomans-Bitter M, van de Wetering M, de Weger R, van Dongen J, Clevers H.Blood. 1995 Oct 15;86(8):3050-9.
- Application Image
- Western Blot
- Immunohistochemistry (Frozen sections)
- Entrez GeneID:
- 6927
- Gene Name:
- HNF1A
- Gene Alias:
- HNF1,LFB1,MODY3,TCF1
- Gene Description:
- HNF1 homeobox A
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene is a transcription factor required for the expression of several liver-specific genes. The encoded protein functions as a homodimer and binds to the inverted palindrome 5'-GTTAATNATTAAC-3'. Defects in this gene are a cause of maturity onset diabetes of the young type 3 (MODY3) and also can result in the appearance of hepatic adenomas. [provided by RefSeq
- Other Designations:
- Interferon production regulator factor (HNF1),albumin proximal factor,hepatic nuclear factor 1,maturity onset diabetes of the young 3,transcription factor 1, hepatic,transcription factor 1, hepatic; LF-B1, hepatic nuclear factor (HNF1), albumin proximal f
- Gene Pathway
- Related Disease
- Albuminuria
- Alzheimer Disease
- Alzheimer disease
- Atherosclerosis
- Autoimmune Diseases
- Body Weight
- Cardiovascular Diseases
- Cleft Lip
- Cleft Palate
- Cognition
- Colorectal Neoplasms
- Coronary Artery Disease
- Coronary Disease
- Diabetes Complications
- Diabetes Mellitus
- Diabetes Mellitus, Type 1
- Diabetes Mellitus, Type 2
- Diabetes, Gestational
- Diabetes, type 1