新冠病毒S2蛋白突变|英国南非巴西突变|SARS-CoV-2 S2 protein (T716I, S982A, D1118H), His Tag
产品名称: 新冠病毒S2蛋白突变|英国南非巴西突变|SARS-CoV-2 S2 protein (T716I, S982A, D1118H), His Tag
英文名称: SARS-CoV-2 S2 protein (T716I, S982A, D1118H), His Tag
产品编号: S2N-C52Hd
产品价格: 0
产品产地: USA
品牌商标: ACROBiosystems
更新时间: null
使用范围: null
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SARS-CoV-2 S2 protein (T716I, S982A, D1118H), His Tag (S2N-C52Hd) is expressed from human 293 cells (HEK293). It contains AA Ser 686 - Pro 1213 (Accession # QHD43416.1). The recombinant protein is expressed from human 293 cells (HEK293) with T4 fibritin trimerization motif and a polyhistidine tag at the C-terminus. Proline substitutions (F817P/ A892P/ A899P/ A942P/ K986P/ V987P) are introduced to stabilize the trimeric prefusion state of SARS-CoV-2 S protein. The T716I/ S982A/ D1118H mutations were identified in the SARS-CoV-2 variant (known as B.1.1.7, 20B/501Y.V1 or VOC 202012/01) which emerged in the United Kingdom.
Molecular Characterization
Molecular Weight:
59.6 kDaPurity:
>95% as determined by SDS-PAGE.Endotoxin:
Less than 1.0 EU per μg by the LAL method.Bioactivity: