FITC标记的核膜糖蛋白210抗体
产品名称： FITC标记的核膜糖蛋白210抗体
英文名称： Anti-GP210/FITC
产品编号： HZ-13495R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： ICC=1:50-200 IF=1:50-200
上海沪震实业有限公司
- 联系人 : 鲍丽雯
- 地址 : 上海市闵行区闵北路88弄1-30号第22幢AQ136室
- 邮编 : 200612
- 所在区域 : 上海
- 电话 : 139****0749 点击查看
- 传真 : 点击查看
- 邮箱 : www.shzbio.net
- 二维码 : 点击查看
Rabbit Anti-GP210/FITC Conjugated antibody
FITC标记的核膜糖蛋白210抗体
| 英文名称 | Anti-GP210/FITC |
| 中文名称 | FITC标记的核膜糖蛋白210抗体 |
| 别 名 | FLJ22389; GP 210; KIAA0906; Nuclear envelope pore membrane protein POM 210; Nuclear pore membrane glycoprotein 210; Nuclear pore protein gp210; Nucleoporin 210; Nucleoporin 210kDa; Nucleoporin Nup210; Nucleoporin210; NUP 210; NUP210; PO210_HUMAN; POM 210; POM210; Pore membrane protein of 210 kDa. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 染色质和核信号 神经生物学 细胞类型标志物 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, |
| 产品应用 | ICC=1:50-200 IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 203kDa |
| 细胞定位 | 细胞膜 |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human GP210 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The nuclear pore complex (NPC) mediates bidirectional macromolecular traffic between the nucleus and cytoplasm in eukaryotic cells and is comprised of more than 100 different subunits. Many of the subunits belong to a family called nucleoporins (Nups), which are characterized by the presence of O-linked-N-acetylglucosamine moieties and a distinctive pentapeptide repeat (XFXFG). gp210, also known as Nup210 (nucleoporin 210kDa) or POM210, is a 1,887 amino acid single-pass type I membrane protein that localizes to both the endoplasmic reticulum and to the nucleus, specifically within the NPC. Expressed ubiquitously with highest expression in pancreas, testis, lung, ovary and liver, gp210 functions as a nucleoporin that is capable of dimerization and is essential for the assembly, fusion and structural integrity of the NPC. gp210 exists as multiple alternatively spliced isoforms and is subject to post-translational phosphorylation. Function: Nucleoporin essential for nuclear pore assembly and fusion, nuclear pore spacing, as well as structural integrity. Subunit: Forms dimers and possibly higher-order oligomers (By similarity). Subcellular Location: Nucleus; nuclear pore complex. Nucleus membrane. Endoplasmic reticulum membrane. Tissue Specificity: Ubiquitous expression, with highest levels in lung, liver, pancreas, testis, and ovary, intermediate levels in brain, kidney, and spleen, and lowest levels in heart and skeletal muscle. Post-translational modifications: N-glycosylated, but not all potential glycosylation sites may be used. Contains high-mannose type oligosaccharides. Phosphorylated at Ser-1881 in mitosis specifically; not phosphorylated in interphase. Similarity: Belongs to the NUP210 family. Database links: UniProtKB/Swiss-Prot: Q8TEM1.3 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
核孔复合物（NPC）介导的双向大交通的细胞核和细胞质之间在真核细胞中，是由超过100个不同的亚基组成。许多亚基属于一种叫做核孔蛋白（婚前），它的特点是o-linked-n-acetylglucosamine部分的存在和独特的五肽重复（XFXFG）。可见，也被称为nup210（核孔蛋白210kda）或pom210，是一个1887个氨基酸的单通I型膜蛋白，定位于内质网和核，特别是在人大。胰腺组织中广泛表达，表达量最高的睾丸、肺、卵巢、肝脏、抗gp210作为核孔蛋白能够二聚化是必不可少的组件，融合和全国人大的结构完整性。G210作为多个交替剪接的亚型A存在。