CDK10 polyclonal antibody
产品名称： CDK10 polyclonal antibody
英文名称： CDK10 polyclonal antibody
产品编号： PAB13668
产品价格： null
产品产地： 台湾
品牌商标： Abnova
更新时间： null
使用范围：
亚诺法生技股份有限公司（Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Goat polyclonal antibody raised against synthetic peptide of CDK10.
- Immunogen:
- A synthetic peptide corresponding to human CDK10.
- Sequence:
- AEPDLECEQIRLK
- Host:
- Goat
- Theoretical MW (kDa):
- 41
- Reactivity:
- Human
- Specificity:
- Approximately 37 KDa band observed in human lung lysates and in lysates of cell lines HEK293, A-549 and HepG2 (calculated MW of 41.0 KDa according to NP_443714.3).
- Form:
- Liquid
- Purification:
- Antigen affinity purification
- Concentration:
- 0.5 mg/mL
- Storage Buffer:
- In Tris saline, pH 7.3 (0.5% BSA, 0.02% sodium azide)
- Storage Instruction:
- Store at -20°C.
Aliquot to avoid repeated freezing and thawing.
- Recommend Usage:
- ELISA (1:64000)
Western Blot (0.5-2 ug/mL)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Identification of CDK10 as an important determinant of resistance to endocrine therapy for breast cancer.
Iorns E, Turner NC, Elliott R, Syed N, Garrone O, Gasco M, Tutt AN, Crook T, Lord CJ, Ashworth A.Cancer Cell. 2008 Feb;13(2):91-104.
- Entrez GeneID:
- 8558
- Protein Accession#:
- NP_443714.3
- Gene Name:
- CDK10
- Gene Alias:
- PISSLRE
- Gene Description:
- cyclin-dependent kinase 10
- Omim ID:
- 603464
- Gene Ontology:
- Hyperlink
- Gene Summary:
- The protein encoded by this gene belongs to the CDK subfamily of the Ser/Thr protein kinase family. The CDK subfamily members are highly similar to the gene products of S. cerevisiae cdc28, and S. pombe cdc2, and are known to be essential for cell cycle progression. This kinase has been shown to play a role in cellular proliferation and its function is limited to cell cycle G2-M phase. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq
- Other Designations:
- CDC2-related protein kinase,cell division protein kinase 10,cyclin-dependent kinase (CDC2-like) 10,cyclin-dependent kinase related protein,serine/threonine protein kinase PISSLRE