MUC1 monoclonal antibody, clone EMA 201
产品名称: MUC1 monoclonal antibody, clone EMA 201
英文名称: MUC1 monoclonal antibody, clone EMA 201
产品编号: MAB6186
产品价格: null
产品产地: 台湾
品牌商标: Abnova
更新时间: null
使用范围:
亚诺法生技股份有限公司(Abnova)
- 联系人 :
- 地址 : 台湾台北市内湖区洲子街 108 号 9 楼
- 邮编 : 11493
- 所在区域 : 台湾
- 电话 : +886-920**1152 点击查看
- 传真 : 点击查看
- 邮箱 : sales@abnova.com.tw
- Specification
- Product Description:
- Mouse monoclonal antibody raised against native MUC1.
- Immunogen:
- Native purified MUC1 from human milk fat globule membranes.
- Host:
- Mouse
- Reactivity:
- Human
- Form:
- Liquid
- Isotype:
- IgG1, kappa
- Storage Buffer:
- In PBS, pH 7.4 (1% BSA, 0.05% sodium azide)
- Storage Instruction:
- Store at 4°C.
- Recommend Usage:
- Immunohistochemistry (1:50-1:200)
The optimal working dilution should be determined by the end user.
- Note:
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Publication Reference
- 1.
- Keratins versus epithelial membrane antigen.
Gown AM.Hum Pathol. 1988 Jan;19(1):119.
- Application Image
- Immunohistochemistry (Formalin/PFA-fixed paraffin-embedded sections)
- Immunohistochemistry (Frozen sections)
- Immunocytochemistry
- Entrez GeneID:
- 4582
- Gene Name:
- MUC1
- Gene Alias:
- CD227,EMA,H23AG,MAM6,PEM,PEMT,PUM
- Gene Description:
- mucin 1, cell surface associated
- Omim ID:
- 158340
- Gene Ontology:
- Hyperlink
- Gene Summary:
- This gene is a member of the mucin family and encodes a membrane bound, glycosylated phosphoprotein. The protein is anchored to the apical surface of many epithelia by a transmembrane domain, with the degree of glycosylation varying with cell type. It also includes a 20 aa variable number tandem repeat (VNTR) domain, with the number of repeats varying from 20 to 120 in different individuals. The protein serves a protective function by binding to pathogens and also functions in a cell signaling capacity. Overexpression, aberrant intracellular localization, and changes in glycosylation of this protein have been associated with carcinomas. Multiple alternatively spliced transcript variants that encode different isoforms of this gene have been reported, but the full-length nature of only some has been determined. [provided by RefSeq
- Other Designations:
- DF3 antigen,H23 antigen,MUC-1/SEC,MUC-1/X,MUC1/ZD,OTTHUMP00000033787,OTTHUMP00000033790,OTTHUMP00000033795,breast carcinoma-associated antigen DF3,episialin,mucin 1,mucin 1, transmembrane,peanut-reactive urinary mucin,polymorphic epithelial mucin,tumor as
- Related Disease
- Adenocarcinoma
- Asthma
- Asthma
- Attention Deficit Disorder with Hyperactivity
- Autistic Disorder
- Breast cancer
- Breast Neoplasms
- Bronchiolitis, Viral
- Carcinoma
- Carcinoma, Squamous Cell
- Chronic Disease
- Disease Susceptibility
- Gastritis
- Gastritis, Atrophic
- Genetic Predisposition to Disease
- Helicobacter Infections
- Infant, Premature, Diseases
- Kidney Failure, Chronic
- Lung Diseases