FITC标记的蛋白酶调解因子7抗体
产品名称： FITC标记的蛋白酶调解因子7抗体
英文名称： Anti-PSMD7/FITC
产品编号： HZ-9366R-FITC
产品价格： null
产品产地： 中国/上海
品牌商标： HZbscience
更新时间： 2023-08-17T10:24:20
使用范围： IF=1:50-200
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Rabbit Anti-PSMD7/FITC Conjugated antibody
FITC标记的蛋白酶调解因子7抗体
| 品编号 | bs-9366R-FITC |
| 英文名称 | Anti-PSMD7/FITC |
| 中文名称 | FITC标记的蛋白酶调解因子7抗体 |
| 别 名 | 26S proteasome non ATPase regulatory subunit 7; 26S proteasome non-ATPase regulatory subunit 7; 26S proteasome regulatory subunit rpn8; 26S proteasome regulatory subunit S12; Moloney leukemia virus 34 proviral integration; MOV 34; MOV 34L; MOV34; Mov34 homolog; Mov34 protein homolog; MOV34L; P40 antibody Proteasome (prosome macropain) 26S subunit non ATPase 7; Proteasome 26S non ATPase subunit 7; Proteasome 26S S12; Proteasome subunit p40; PSD7_HUMAN; PSMD 7; PSMD-7; PSMD7; S12 antibody. |
| 规格价格 | 100ul/2980元 购买 大包装/询价 |
| 说 明 书 | 100ul |
| 研究领域 | 细胞生物 信号转导 表观遗传学 |
| 抗体来源 | Rabbit |
| 克隆类型 | Polyclonal |
| 交叉反应 | Human, Mouse, Rat, Chicken, Dog, Pig, Cow, Rabbit, Sheep, |
| 产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
| 分 子 量 | 37kDa |
| 性 状 | Lyophilized or Liquid |
| 浓 度 | 1mg/ml |
| 免 疫 原 | KLH conjugated synthetic peptide derived from human PSMD7 |
| 亚 型 | IgG |
| 纯化方法 | affinity purified by Protein A |
| 储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
| 保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
| 产品介绍 | background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a non-ATPase subunit of the 19S regulator. A pseudogene has been identified on chromosome 17. Function: Acts as a regulatory subunit of the 26S proteasome which is involved in the ATP-dependent degradation of ubiquitinated proteins. Subunit: Homodimer. Interacts with TRIM5. Similarity: Belongs to the peptidase M67A family. Contains 1 MPN (JAB/Mov34) domain. Database links: Entrez Gene: 5713 Human Entrez Gene: 17463 Mouse Entrez Gene: 307821 Rat Omim: 157970 Human SwissProt: Q3ZBD0 Cow SwissProt: P51665 Human SwissProt: P26516 Mouse Unigene: 440604 Human Unigene: 18347 Mouse Unigene: 20659 Rat Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
26S蛋白酶体是由2个复合物、20S核心和19S调节器组成的高度有序结构的多金属蛋白酶复合物。20S核由28个不相同的亚基组成的4个环，2个环由7个α亚基组成，2个环由7个β亚基组成。19S调节剂由一个碱基组成，它含有6个ATPase亚基和2个非ATP酶亚基，和一个含有最多10个非ATPase亚基的盖子。蛋白酶体在高浓度的真核细胞中分布，在非溶酶体途径中ATP／泛素依赖的过程中裂解肽。一种修饰的蛋白酶体，免疫蛋白酶体的基本功能，是I类MHC肽的加工。该基因编码19-S调节器的非ATP酶亚基。在第17号染色体上已鉴定出假基因。