FITC标记的同源盒蛋白HOXB13抗体
产品名称: FITC标记的同源盒蛋白HOXB13抗体
英文名称: Anti-HOXB13/FITC
产品编号: HZ-2561R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-HOXB13/FITC Conjugated antibody
FITC标记的同源盒蛋白HOXB13抗体
英文名称 | Anti-HOXB13/FITC |
中文名称 | FITC标记的同源盒蛋白HOXB13抗体 |
别 名 | Homeo box B13; Homeobox B13; Homeobox protein Hox B13; Homeobox protein Hox-B13; Homeobox protein HoxB13; HOX B13; HOXB 13; HOXB13; HXB13_HUMAN; PSGD; PSGD protein. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 肿瘤 细胞生物 免疫学 染色质和核信号 信号转导 生长因子和激素 转录调节因子 肿瘤细胞生物标志物 表观遗传学 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Dog, Pig, Horse, Rabbit, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 31kDa |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human PSGD |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: This gene encodes a transcription factor that belongs to the homeobox gene family. Genes of this family are highly conserved among vertebrates and essential for vertebrate embryonic development. This gene has been implicated to play a role in fetal skin development and cutaneous regeneration. In mice, a similar gene was shown to exhibit temporal and spatial colinearity in the main body axis of the embryo, but was not expressed in the secondary axes, which suggests functions in body patterning along the axis. This gene and other HOXB genes form a gene cluster at chromosome the 17q21-22 region. [provided by RefSeq, Jul 2008]. Function: Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Subcellular Location: Nucleus. Similarity: Belongs to the Abd-B homeobox family. Contains 1 homeobox DNA-binding domain. Database links: Entrez Gene: 10481 Human Entrez Gene: 15408 Mouse Entrez Gene: 303480 Rat Omim: 604607 Human SwissProt: Q92826 Human SwissProt: P70321 Mouse Unigene: 66731 Human Unigene: 57221 Mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications. HOXB13存在于很多哺乳动物的内分泌腺,但在人的前列腺癌及乳腺癌中表达量较高 |
该基因编码属于同源盒基因家族的转录因子。这一家族的基因在脊椎动物中高度保守,对脊椎动物胚胎发育至关重要。这一基因已被牵连在胎儿皮肤发育和皮肤再生发挥作用。在小鼠中,一个相似的基因被显示在胚胎的主体轴上表现出时间和空间共线性,但在二次轴中没有表达,这表明沿着轴的身体图案化的功能。该基因和其他HOXB基因在17q21-22区域的染色体上形成一个基因簇。[ RefSeq,JUL 2008 ]提供。