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Interleukin 13 Receptor Alpha 1 ( IL13RA1 / CD213a1 ) Antibody
 
 
 
 
 
 
 
 
 
Order or Inquire for IL13RA1 Antibody product
 
 
 
 
 
 
 
Detection limit is 0.125 ng/lane in WB
 
 
 
 
 
 
 
 
 
 
IL13RA1 / CD213a1 抗体产品信息
 
 
 
 
免疫原 : 
 
 
Recombinant human IL13RA1 protein  ( Catalog#10943-H08H )
 
 
 
 
Antibody Type : 
 
Rabbit Monoclonal Antibody ( Rabbit mAb Service Platform )
 
 
 
 
克隆号 :
 
 
38
 
 
 
抗体宿主 :
 
 
Rabbit IgG
 
 
 
 
缓冲液 :
 
0.2 μm filtered solution in PBS with 5% trehalose
 
 
 
制备方法 : 
 
 
This antibody was obtained from a rabbit immunized with purified, human cell-derived, recombinant human IL13RA1 extracellular domain ( rh IL13RA1 ; Catalog#10943-H08H ; NP_001551.1 ; Met 1 - Thr 343 ).
 
 
 
 
 
IL13RA1 / CD213a1 Antibody Usage Guide
 
 
 
 
 
特异性 : 
 
 
 
Human IL13RA1 / CD213a1 
 
 
 
 
 
 
 
No cross-reactivity in ELISA with
 
Mouse IL13RA1 / CD213a1
 
Human IL13RA2 / IL13R
 
Human IL4R / IL4Ra / CD124
 
Human CSF2RB / CD131
 
Human cell lysate (293 cell line)
 
 
 
 
Western blot : 
 
This antibody can be used at 1 - 2 μg/mL with the appropriate secondary reagents to detect human IL13RA1 in WB. Using a DAB detection system, the detection limit for human IL13RA1 is approximately 0.125 ng/lane under non-reducing conditions and reducing conditions
 
 
 
储存方法 :
 
This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -70℃. Preservative-Free.
 Sodium azide is recommended to avoid contamination (final concentration 0.05%-0.1%). It is toxic to cells and should be disposed of properly. Avoid repeated freeze-thaw cycles.
 
 
 
 
IL13RA1 / CD213a1 Antibody Related Products & Topics
 
 
相关领域:
 
Stem Cell>>Hematopoietic Stem Cell (HSC)>>Hemangioblast>>Endothelial Cell Marker>>IL-13RA1/CD213a1
 
Cancer>>Angiogenesis>>Cytokines/Chemokines in Angiogenesis>>IL-13RA1/CD213a1
 
Immunology>>Cytokine & Receptor>>Interleukin & Receptor>>Other>>IL-13RA1/CD213a1
 
Immunology>>Cluster of Differentiation>>B Cell CD Antigen>> IL-13RA1/CD213a1
 
Immunology>>Cluster of Differentiation>>Monocyte/Macrophage CD Antigen>>Monocyte Markers>>IL-13RA1/CD213a1
 
Immunology>>Cluster of Differentiation>>T Cell CD Antigen>>Helper T Cells>>IL-13RA1/CD213a1
 
Proteins:
 
 
 
 
Molecule
 
Species
 
Description //For Detailed Info. and Price------CLICK!
 
Cat No
 
 
 
IL-13RA1/CD213a1
 
Human
 
 IL-13RA1/CD213a1/Fc Protein, Recombinant
 
10943-H03H
 
 
 
IL-13RA1/CD213a1
 
Human
 
IL-13RA1/CD213a1 Protein, Recombinant
 
10943-H08H
 
 
 
IL-13RA1/CD213a1
 
Mouse
 
 IL-13RA1/CD213a1/Fc Protein, Recombinant
 
50088-M03H
 
 
 
IL-13RA1/CD213a1
 
Mouse
 
 IL-13RA1/CD213a1 Protein, Recombinant
 
50088-M08H
 
 
 
 
Antibodies:
 
 
 
 
Molecule
 
Application
 
Description //For Detailed Info. and Price------CLICK!
 
Cat No
 
 
 
Human 
 IL-13RA1/CD213a1
 
WB, ELISA
 
IL13RA1 Antibody, Mouse MAb
 
10943-MM06
 
 
 
Human 
 IL-13RA1/CD213a1
 
ELISA
 
IL13RA1 Antibody, Rabbit MAb
 
10943-R026
 
 
 
Human 
 IL-13RA1/CD213a1
 
WB
 
IL13RA1 Antibody, Rabbit MAb
 
10943-R038
 
 
 
Human 
 IL-13RA1/CD213a1
 
WB, ELISA
 
Rabbit Polyclonal Antibody
 
10943-RP01
 
 
 
Human 
 IL-13RA1/CD213a1
 
WB, ELISA
 
Rabbit Polyclonal Antibody (Antigen Affinity Purified)
 
10943-RP02
 
 
 
Mouse 
 IL-13RA1/CD213a1
 
WB, ELISA
 
Rabbit Polyclonal Antibody
 
50088-RP01
 
 
 
Mouse 
 IL-13RA1/CD213a1
 
WB, ELISA
 
Rabbit Polyclonal Antibody (Antigen Affinity Purified)
 
50088-RP02
 
 
 
 
 
IL13RA1 / CD213a1 抗体背景综述
 
 
Interleukin 13 receptor alpha 1 (IL13Rα1), also known as CD213A1 (cluster of differentiation 213A1), is a subunit of the IL-13 receptor, and binds IL13 with a low affinity by itself. IL-13 is capable of binding two types of receptor: the heterodimer, composed of the IL13 Rα1 and the IL4Rα , transducing the IL13 signals; and the IL13Rα2, acting as a nonsignaling "decoy" receptor. IL13 Rα1 forms a functional receptor complex for IL-13 with IL4 receptor alpha (IL4Rα), a subunit shared by IL13 and IL4 receptors, transducing an IL13-dependent proliferative signal. IL13 Rα1 has also been shown to serve as an alternate accessory protein to the common cytokine receptor gamma chain for IL4 signaling, but cannot replace the function of gamma C in allowing enhanced IL2 binding activity. The human IL13 Rα1 cDNA encodes a 427 aa residue precursor protein, and the extracellular domain is composed of three fibronectin type III domains, D1, D2, and D3, of which the last two comprise the cytokine receptor homology modules (CRHs). Human and mouse IL13 Rα1 share 76% aa sequence identity.
 
 
参考文献
 
 
 
Caput, D. et al., 1996, J. Biol. Chem. 271:16921-6.
 
Hilton, D.J. et al., 1996, Proc. Natl. Acad. Sci. USA 93:497-501.
 
Zhang, JG. et al., 1997, J. Biol. Chem. 272:9474-80.
 
Donaldson, DD. et al., 1998, J. Immunol. 161:2317-24.
 
Orchansky, PL. et al.,1999, J. Biol. Chem. 274 (30): 20818-25.