FITC标记的三磷酸腺苷结合盒转运蛋白A亚基5抗体
产品名称: FITC标记的三磷酸腺苷结合盒转运蛋白A亚基5抗体
英文名称: Anti-ABCA5/FITC
产品编号: HZ-7940R-FITC
产品价格: null
产品产地: 中国/上海
品牌商标: HZbscience
更新时间: 2023-08-17T10:24:20
使用范围: IF=1:50-200
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Rabbit Anti-ABCA5/FITC Conjugated antibody
FITC标记的三磷酸腺苷结合盒转运蛋白A亚基5抗体
英文名称 | Anti-ABCA5/FITC |
中文名称 | FITC标记的三磷酸腺苷结合盒转运蛋白A亚基5抗体 |
别 名 | ABC13; ATP binding cassette sub family A (ABC1) member 5; ATP binding cassette A5; ATP binding cassette sub family A member 5; DKFZp451F117; DKFZp779N2435; EST90625; FLJ16381; KIAA1888; ABCA5_HUMAN. |
规格价格 | 100ul/2980元 购买 大包装/询价 |
说 明 书 | 100ul |
研究领域 | 细胞生物 细胞周期蛋白 转录调节因子 |
抗体来源 | Rabbit |
克隆类型 | Polyclonal |
交叉反应 | Human, Mouse, Rat, Sheep, |
产品应用 | IF=1:50-200 not yet tested in other applications. optimal dilutions/concentrations should be determined by the end user. |
分 子 量 | 186kDa |
细胞定位 | 细胞膜 |
性 状 | Lyophilized or Liquid |
浓 度 | 1mg/ml |
免 疫 原 | KLH conjugated synthetic peptide derived from human ABCA5 |
亚 型 | IgG |
纯化方法 | affinity purified by Protein A |
储 存 液 | 0.01M TBS(pH7.4) with 1% BSA, 0.03% Proclin300 and 50% Glycerol. |
保存条件 | Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C. |
产品介绍 | background: ABCA5 is a member of the superfamily of ATP binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). ABCA5 is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. ABCA5 is localized in the lysosome, late endosome and Golgi apparatus membrane and is thought to play a role in the processing of autolysosomes. Function: May play a role in the processing of autolysosomes (By similarity). Subcellular Location: Lysosome membrane; Multi-pass membrane protein. Late endosome membrane; Multi-pass membrane protein. Golgi apparatus membrane; Multi-pass membrane protein (By similarity). Tissue Specificity: Ubiquitously expressed. Highly expressed in testis, skeletal muscle, kidney, liver and placenta. Post-translational modifications: N-glycosylated (By similarity). Similarity: Belongs to the ABC transporter superfamily. ABCA family. Contains 2 ABC transporter domains. Database links: UniProtKB/Swiss-Prot: Q8WWZ7.2 Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications |
ABCA5是ATP结合盒(ABC)转运蛋白超家族的成员。ABC蛋白通过跨膜和胞内膜运输各种分子。ABC基因分为七个不同的亚家族(ABC1、MDR/TAP、MRP、ALD、OABP、GCN20和White)。ABCA5是ABC1亚家族的成员。ABC1亚家族成员是唯一发现于多细胞真核生物中的唯一的主要ABC亚科。ABCA5定位于溶酶体、晚期内体和高尔基体膜,并被认为在自体溶酶体的加工中起作用。